Sign in now if you're a subscriber.
Only three biochemical tests — urinary free cortisol, plasma corticotropin, and plasma cortisol measurements — are needed to distinguish patients with Cushing’s syndrome from those with obesity or the metabolic syndrome.
Disclosure forms provided by the author are available with the full text of this article at NEJM.org.
No potential conflict of interest relevant to this article was reported.
From the Division of Endocrinology, Diabetes, and Clinical Nutrition, Oregon Health and Science University, Portland.
Address reprint requests to Dr. Loriaux at the Division of Endocrinology, Diabetes, and Clinical Nutrition, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd., L607, Portland, OR 97239-3098, or at firstname.lastname@example.org.